News : Findings prompt more research into anti-HIV gel

CAPE TOWN — The Department of Science and Technology has lent its support to further research into a tenofovir-based gel for preventing HIV infection among women, hoping the investment will ultimately see SA developing the capacity to manufacture and export the product.



Pharmaceutical imports are the fifth-biggest contributor to SA’s trade deficit, so the government is keen to find ways to make more of these goods in SA.

Local production also improves security of supply.

The Technology Innovation Agency has a licence from the US research organisation Conrad for the African rights to a microbicide containing tenofovir gel, and has an agreement with local firm Cipla Medpro to manufacture and distribute the product should it prove safe and effective.

Yesterday Deputy Science and Technology Minister Derek Hanekom and US ambassador Donald Gips announced a bilateral initiative to support a phase 3 trial of a microbicide containing the AIDS drug tenofovir.

The department has provided R70m for the study, called Follow- on African Consortium for Tenofovir Studies (FACTS), while the US Agency for International Development (USAID) has committed $18m.

The study seeks to confirm the findings of the Caprisa 004 trial, announced last year. Caprisa 004 was a phase 2b study, involving 900 women from two sites in KwaZulu-Natal. It found that a microbicide containing 1% tenofovir, if used before and after sex, reduced the chances of women contracting HIV by 39%. The gel also halved the risk of contracting herpes, a viral infection that increases vulnerability to HIV.

But the findings had a wide margin of error, with the efficacy of HIV protection estimated to lie between 6% and 60%, said FACTS protocol chair Prof Helen Rees. A larger trial was needed to confirm the Caprisa trial and satisfy regulators of the gel’s safety and efficacy, she said.

An unexpected finding was increased sexual pleasure.

"One of the big messages we got, was many women said ‘We liked this.’" Most of the feedback during that study had come from women in their menopause. If the gel proved successful, the sexual pleasure factor could be a marketing option. Source BUSINESS DAY

Rating: 0.00 (0 votes) - Rate this News -

Tags: and   of   HIV   The   Science   Department   Technology  


Other articles
2015/1/21 13:51:40 - All About That Bass: Research Shows That Curvier Women Produce More Intelligent Kids
2014/7/17 12:09:35 - Typhoon Kills 38 In The Philippines
2014/7/9 11:54:07 - What Did Jay Z Do? Woman Who Abandoned Baby In A Subway, Arrested And Shouts F*ck Shawn Corey Carter
2014/7/9 8:34:21 - Man Chokes And Die During Eating Contest
2014/7/7 14:08:19 - Neymar Causes Panic In His Camp
2014/7/7 13:12:37 - 60 Girls Escape Boko Haram Captors
2014/7/4 8:30:00 - 56 Year Old Woman Chases A 25 Year Old Man With A Knife After He Refused To Have Sex With Her.
2014/7/2 8:50:00 - Bless Her For Trying: ANC MP Wants SABC To Play The National Anthem Twice Daily
2014/7/1 12:54:37 - Touch Him Lord: Florida Church Holds Prayer For LeBron James Do The “Right Thing”
2014/6/30 10:08:39 - OP Trial Back On After Month Long Psychiatric Evaluation
2014/6/23 15:50:00 - Shady Senior Citizeans: 102 Years Old Grandma Killed Roommate Over A Bed?
2014/6/23 9:19:25 - Illegal Miners Killed, Cops Searching For The Killers
2014/6/18 9:16:31 - Mexico Proves To Be Tough Competitor Against Host Nation Brazil In A 0-0 Draw
2014/6/18 8:56:27 - Morethan 60 People Missing After An OverLoaded Boat Sinks Off Malaysia
2014/6/17 15:31:41 - You’re Hired: First Daughter Malia Obama Gets Her First Job At 16



Bookmark this article at these sites

                   

 
The comments are owned by the poster. We aren't responsible for their content.
2010 Abuse ANC and Anni Apple avatar Bafana Barack Britain Cape China crime Cup Dewani Eskom facebook FIFA Gaga Google Haiti HIV Internet iPad Jackson Jub Malema Manchester Mandela MaNtuli Michael Nelson New Obama of Oprah Prince Shrien SWC The tickets Tiger Transnet twitter United Winfrey Woods World Zapiro Zuma
Powered by Sevafrica
None All Errors (1) Deprecated (0) Queries (37) Blocks (10) Extra (2) Timers(6)
Errors
Warning: XoopsEditorHandler::getList() should not be called statically. in file /class/xoopseditor/xoopseditor.php line 171
Deprecated
Queries
0.000467 - SET NAMES 'utf8'
0.000369 - SET SQL_BIG_SELECTS = 1
0.000257 - SELECT * FROM config WHERE (conf_modid = '0' AND conf_catid = '1') ORDER BY conf_order ASC
0.000698 - SELECT sess_data, sess_ip FROM session WHERE sess_id = 'rm83914jjpm0csb92lppp1qf02'
0.000320 - SELECT * FROM modules WHERE dirname = 'news'
0.000369 - SELECT COUNT(*) FROM group_permission WHERE (gperm_modid = '1' AND (gperm_groupid = '3') AND gperm_name = 'module_read' AND gperm_itemid = '32')
0.000215 - SELECT * FROM config WHERE (conf_modid = '32') ORDER BY conf_order ASC
0.000320 - SELECT * FROM modules WHERE dirname = 'protector'
0.000908 - DELETE FROM protector_access WHERE expire < UNIX_TIMESTAMP()
0.000743 - SELECT COUNT(*) FROM protector_access WHERE ip='54.198.23.251' AND request_uri='/modules/news/article.php?storyid=1934'
0.000556 - SELECT COUNT(*) FROM protector_access WHERE ip='54.198.23.251'
0.000612 - INSERT INTO protector_access SET ip='54.198.23.251',request_uri='/modules/news/article.php?storyid=1934',expire=UNIX_TIMESTAMP()+'60'
0.000986 - SELECT s.*, t.* FROM stories s, topics t WHERE (storyid=1934) AND (s.topicid=t.topic_id)
0.000340 - SELECT COUNT(*) FROM group_permission WHERE (gperm_modid = '32' AND (gperm_groupid = '3') AND gperm_name = 'news_view' AND gperm_itemid = '1')
0.000657 - UPDATE stories SET counter = counter+1 WHERE storyid = 1934
0.000520 - SELECT COUNT(*) FROM banner
0.000616 - SELECT * FROM banner LIMIT 0, 1
0.000733 - UPDATE banner SET impmade = impmade+1 WHERE bid = 1
0.000192 - SELECT * FROM config WHERE (conf_modid = '0' AND conf_catid = '3') ORDER BY conf_order ASC
0.000409 - SELECT DISTINCT gperm_itemid FROM group_permission WHERE gperm_name = 'block_read' AND gperm_modid = 1 AND gperm_groupid IN (3)
0.000202 - SELECT b.* FROM newblocks b, block_module_link m WHERE m.block_id=b.bid AND b.isactive=1 AND b.visible=1 AND m.module_id IN (0,32) AND b.bid IN (415,414,413,396,395,394,380,379,378,377,376,375,374,373,372,371,370,369,368,367,366,365,364,360,362,361,480,481,363,356,477,355,354,353,357,358,359,352,351,350,349,348,347,346,344,343,345,339,340,341,342,338,337,463,335,334,333,332,330,329,328,327,326,331,325,324,323,320,319,318,321,322,317,316,313,312,311,314,315,306,305,304,307,308,309,310,202,201,200,199,198,197,195,194,193,192,191,190,189,188,187,186,185,181,182,183,184,168,154,153,157,169,171,172,173,178,158,170,167,155,156,166,161,160,159,196,134,133,132,131,130,129,128,127,126,125,124,123,122,121,120,119,118,117,116,109,110,111,476,482,478,479,485,483,77,52,51,53,54,15,14,13,12,11,10,9,8,7,6,5,4,3,2,1,411,410,409,408,407,406,405,403,402,563,404,401,399,398,393,391,390,389,388,387,386,385,384,412,383,382,381,294,293,292,291,290,289,288,210,207,206,205,204,203,179,135,112,208,209,562,115,136,180,68,67,39,303,17,16,416,417,418,421,422,423,426,427,428,429,434,435,436,437,438,439,440,441,442,443,444,518,446,447,448,449,450,451,454,455,456,457,458,459,460,461,462,464,465,466,467,468,469,470,471,472,473,474,475,513,487,488,489,490,491,492,493,494,512,511,496,497,498,499,500,501,502,503,504,505,506,507,508,515,510,516,520,521,522,523,524,525,526,527,528,529,530,531,532,533,534,535,536,537,550,539,540,541,542,543,544,545,546,548,549,551,552,553,554,555,556,557,558,559,560,561,564) ORDER BY b.weight, m.block_id
0.000399 - SELECT * FROM modules WHERE dirname = 'tag'
0.000260 - SELECT * FROM config WHERE (conf_modid = '63') ORDER BY conf_order ASC
0.000283 - SELECT DISTINCT(o.tag_id), o.tag_term, o.tag_status, SUM(l.tag_count) AS count, l.tag_modid FROM tag_tag AS o LEFT JOIN tag_stats AS l ON l.tag_id = o.tag_id WHERE (o.tag_status = '0') GROUP BY o.tag_id ORDER BY count DESC LIMIT 0, 50
0.000300 - SELECT * FROM smiles
0.000974 - SELECT * FROM stories_files WHERE storyid=1934
0.001537 - SELECT s.*, t.* FROM stories s, topics t WHERE (s.published > 0 AND s.published <= 1537831546) AND (s.expired = 0 OR s.expired > 1537831546) AND (s.topicid=t.topic_id) AND s.ihome=0 ORDER BY s.published DESC LIMIT 0, 15
0.000961 - SELECT storyid, title FROM stories WHERE (published > 0 AND published <= 1537831546) AND (expired = 0 OR expired > 1537831546) AND storyid > 1934 ORDER BY storyid ASC LIMIT 0, 1
0.000773 - SELECT storyid, title FROM stories WHERE (published > 0 AND published <= 1537831546) AND (expired = 0 OR expired > 1537831546) AND storyid < 1934 ORDER BY storyid DESC LIMIT 0, 1
0.000276 - SELECT * FROM topics ORDER BY topic_title
0.000345 - SELECT * FROM config WHERE (conf_modid = '0' AND conf_catid = '5') ORDER BY conf_order ASC
0.000315 - SELECT * FROM config WHERE (conf_modid = '0' AND conf_catid = '3') ORDER BY conf_order ASC
0.002252 - SELECT o.tag_id, o.tag_term FROM tag_link AS l LEFT JOIN tag_tag AS o ON o.tag_id = l.tag_id WHERE l.tag_itemid = 1934 AND l.tag_modid = 32 ORDER BY o.tag_count DESC
0.000294 - SELECT COUNT(*) FROM group_permission WHERE (gperm_modid = '1' AND (gperm_groupid = '3') AND gperm_name = 'system_admin' AND gperm_itemid = '14')
0.000269 - SELECT COUNT(*) FROM group_permission WHERE (gperm_modid = '32' AND (gperm_groupid = '3') AND gperm_name = 'news_submit')
0.000920 - SELECT COUNT(*) as cpt FROM topics WHERE menu=1
0.003009 - SELECT * FROM xoopscomments WHERE (com_modid = '32' AND com_itemid = '1934' AND com_pid = '0') ORDER BY com_id ASC
Total: 37
Blocks
User Menu: Not cached
Search: Not cached
Custom Block (HTML): Not cached
Custom Block (HTML): Not cached
Custom Block (HTML): Not cached
Custom Block (HTML): Not cached
Cumulus Tag Cloud: Not cached
Custom Block (HTML): Not cached
Custom Block (HTML): Not cached
Custom Block (HTML): Not cached
Total: 10
Extra
Included files: 118 files
Memory usage: 8997744 bytes
Timers
XOOPS took 0.123 seconds to load.
XOOPS Boot took 0.033 seconds to load.
Module init took 0.018 seconds to load.
XOOPS output init took 0.024 seconds to load.
Module display took 0.042 seconds to load.
Page rendering took 0.005 seconds to load.